Cristina is bothered by a new year's mandatory work limit. Meanwhile, multiple pre-op patients develop infections, causing one doctor to wonder if she is at fault. As the hospital deals with Meredith's trauma, Callie and Maggie perform a risky, experimental surgery on Alex's year-old patient against his professional opinion.
Meanwhile, Owen and Nathan are still at odds with each other, and Maggie and Andrew's relationship continues to develop. She knows someone on the staff. Meanwhile, Oliver continues to charm Marissa and throws his weight around by inviting her, Ryan, Seth, Summer, Anna and Luke to a rock concert where the band Rooney is playing. Things take another when when Caleb makes a marriage proposal to Julie, which sparks anger and a feeling of betrayal for Luke who gets behind the wheel of his car and has a near-fatal accident. Many new people guest star in the course of Addison's road trip to California.
Audible Download Audio Books. At the same time, Seth insists he has two Godly forces helping him as he continues to play both Summer and Anna by claiming he has chosen the other. Later, Ryan's mother, Dawn, makes a surprise visit to Newport, and things don't go quite as she and Ryan may have planned due to her constant drinking. The hospital gets inundated with flu infected patients, which causes the doctors to slowly fall ill one by one. Blair and Louis return from Monaco and begin planning their royal wedding, but when Louis refuses to stand up to his family and support Blair's choices, his weakness threatens their relationship.
Meanwhile the interns all keep careful watch on the family of premature quintuplets with a variety of serious health challenges, Izzie's anger at Alex reaches boiling point, and Dr. Meanwhile Derek has to come face to face with a former patient's husband in a wrongful death deposition, and spending time with a heart patient's daughter opens up some old wounds for Cristina. Hitting the staff hard, they all find unique ways to get through the various stages of grief.
The clinical trial continues to make progress. Richard tries to get information from Addison about a family member's condition. Meanwhile, Ryan and Seth discover the romantic connection between Luke and Marissa's mother in which Ryan persuades Luke to break it off before Marissa finds out. Bailey puts George on an impossible case. Mark and Lexie cope with an arrival of a woman from his past.
Izzie pushes the boundaries of her probation. Derek tests the Chief's authority when Richard objects to moving forward with the risky surgery. The hospital staff is left to deal with the aftermath of George's passing. Meanwhile, Callie stresses while preparing for her first date with Erica.
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Meanwhile, free dating Meredith makes a life changing decision and one doctor receives shocking news. Ryan has a difficult stay in a Juvenile Hall prison for the arson charge. She doesn't want medicine to take away the pain from her injury so not to put her baby's growth in jeopardy.
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Adele wants Addison to keep a secret from Richard. The survivors from the crash are asked to make an almost impossible decision that will affect the rest of their lives. George's father has a serious heart problem that requires surgery and George chooses Burke to do the procedure. Almost everyone searches for Meredith while they ponder her place in the world. We meet a boss, his assistant, and his wife.
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- Everyone is struggling after losing one of their own and are turning to any distraction they can find.
- Meanwhile the hospital is abuzz as Mark attempts a rare face transplant surgery.
- All of the interns are in awe when a woman comes in with a record breaking tumor, but it is so far advanced that the woman's prognosis is not good.
- But things don't go well for everyone, except for Oliver when his erratic behavior begins showing itself to Ryan and Luke, but Marissa brushes it off as just playful behavior.
- At the party, Meredith and Derek get caught together by Dr.
- Someone goes to a bed-and breakfast.
- Some of the women form a club based on an experience they all share.
- Denny has an outburst at Izzie and Derek has an outburst at Meredith.
Derek and Mark's opinions clash when the try to decide the course of treatment for a burn victim. This episode is the second part of a two-hour season finale. Also Izzie and Alex may be creating some heat. Meredith is devastated by the latest blow to her love life. Richard is desperate for Derek and Meredith to accept Adele into their Alzheimer's trial, but will Adele stand in her own way?
Lily throws Charlie a party to officially introduce her to New York society. The Chief officially announces his intention to retire to the administration of Seattle Grace and to Adele. Derek and Rose have been dating and Meredith has noticed the activities of her current off-again ex-boyfriend. Meredith and Cristina relate at Emerald City Bar about what dating their respective attendings is like. Meanwhile, Sandy gives Seth some sex advice over his dating of Summer.
Meanwhile, a familiar face returns to the hospital. The video features clips from the previous three seasons and the episode will feature a glimpse at the new season of Grey's Anatomy. The staff is trying to deal with antsy patients while dealing with a major disaster when a cargo ship strikes a Ferryboat in Seattle. Meanwhile, friction between Owen and Amelia makes for an uncomfortable working situation for Stephanie.
Shane's case induces a spreading fascination among the staff. Meanwhile, Richard calls on Dr. Other news includes patients doing uncanny things and relationship havoc being wrecked between the doctors, as per usual. Meanwhile, good nickname online dating the chief reluctantly tells Dr.
Now that Bailey knows about Meredith and Derek's affair, their jobs are in jeopardy, and she advises Meredith to end it. Meredith and Cristina lie to each other and themselves about their relationships with McDreamy and Burke, respectively. Meanwhile, Catherine springs into action when a man is brought into the hospital after his wife seeks revenge on his cheating ways. George faces more problems with Callie and Izzie.
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Burke has a patient who inspires him to talk to Meredith and Cristina about doing what they say they will. Someone ends up on the brink of death. Among the new interns are George, forced to repeat his internship after failing his exams, and Lexie Grey, Meredith's half-sister. Nate takes on a new role at the Spectator, but his first big story turns out to be about someone he knows all too well. Meredith, Derek, and Addison sarcastically take another small stab at their friendships.
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Cristina is in a good mood although Alex, Izzie, George, and Meredith are having problems but in the meantime Burke hasn't forgiven Cristina for her late night faux pas. Meanwhile, Callie makes a bold decision regarding her relationship with Arizona, and tragic news brings the doctors together. Cristina looks to Meredith for advice as she assesses her future at the hospital. Meanwhile Catherine tells Richard that one of his residents has failed.
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One doctor's overreaction unites two bickering patients. Meredith and Derek's clinical trial experiences one or two developments. Derek sorts through what kissing Rose means. Also, Ryan and Luke confront Marissa and force her to choose one of them. Meanwhile, official dating the hospital implements new policies which test the patience of the staff.
Callie rushes to be with George after she learns that his dad needs an emergency procedure. Addison is continuing to own Alex and he's upset about it. Meredith has more confusing and uncomfortable encounters with members of her family.
Meanwhile, Izzie empathizes with a patient riddled with tumors, as Mark, annoyed with Cristina's competitive zeal, tricks her into assisting on an unusual surgery. The much-anticipated th episode will open with a musical dream sequence featuring Serena, Blair and all the men in their lives. Meanwhile, Richard leans on Bailey for advice.